Curriculum R. Costa
Rossella Costa
Napoli, Italy 14/10/1982
Italian Citizen
Sapienza Univeristy of Rome, Department of Biology and Biotechnology “Charles Darwin”, P.le Aldo Moro 5, Rome, Italy/ Department of Molecular Medicine, Viale Regina Elena 324, Rome, Italy/
Phone number: (+39) 06/49912849
Fax: (+39) 06/4456866
E-mail: [email protected]; [email protected]
WORK EXPERIENCE
OCTOBER 2010/TODAY: Research activity. Telethon Post Doctoral fellowship. Sapienza University of Rome Department of Molecular Medicine. Research work: Characterization of a mouse transgenic model of a tissue-specific expression of the GsαR201Cgene
JUNE 2010/TODAY: external collaboration to the Medical Encyclopedia, Curcio Editor
OCTOBER 2009/2010: Research activity. Post-Doctoral fellowship. Sapienza University of Rome. Department of Biology and Biotechnology “Charles Darwin”. Research work: characterization of CD146 downregulated transgenic mice and investigation of potential ligands of CD146 through the screening of a random phage library
JULY 2009: External collaboration to the “La Scienza in rete” web magazine
http://www.scienzainrete.it
JUNE 2009/TODAY: Member of the editorial staff of “Orizzonti Biotecnologici” web magazine
OCTOBER 2006-OCTOBER 2009: Research activity. PhD fellowship in Genetics and Molecular Biology. Sapienza University of Rome. Department of Biology and Biotechnology “Charles Darwin”. Research work: characterization of CD146 downregulated transgenic mice and investigation of potential ligands of CD146 through the screening of a random phage library
OCTOBER 2004/OCTOBER 2006: Research activity. Research work: Evaluation of protein-protein and protein-DNA interactions through Chromatin. Immunoprecipitation, RNA interference and biochemical assays.
EDUCATION AND TRAINING
OCTOBER 2010/TODAY: Post Doctoral fellow. Supervisor: Prof. Paolo Bianco and prof.ssa Isabella Saggio. Sapienza University of Rome. Department of Molecular Medicine
OCTOBER 2006/OCTOBER 2009: PhD student. Sapienza University of Rome. Department of Biology and Biotechnology “Charles Darwin”. Thesis title The role of the stem cell marker, melanoma cell adhesion molecule MCAM/CD146. Supervisor: Prof.Isabella Saggio. PhD coordinator: Prof. Irene Bozzoni
OCTOBER 2004/OCTOBER 2006: Master Degree in Medical Biotechnology with full marks 110 cum laudem. University of Naples “Federico II”. Department of Biochemistry and biotechnologies. Thesis Title: “PRMT5 cooperates to transcriptional repression of the Aldolasi A gene trough the intercation with ZNF224 protein”. Supervisor: Prof. Paola Costanzo
OCTOBER 2001/OCTOBER 2004: Bachelor Degree in Medical Biotechnology with full marks 110/110. University of Naples “Federico II” – Department of Biochemistry and biotcnologies. Thesis Title: “The transcriptional repressor ZNF224 interacts with the Wilms tumour WT1”. Supervisor: Prof. Paola Costanzo
JULY 2001: Maturità classica (High School Degree). Liceo “G. De Bottis”, Torre Del Greco, Naples, Italy.
School leaving exam with full marks 100/100
LANGUAGES
Italian (Mother tongue)
English (UPPER INTERMEDIATE B2)
CERTIFICATIONS
JUNE 2009: FCE
TECHNICAL SKILLS AND COMPETENCES
Cell Cultures and Cell Transfection
Isolation of stromal stem cells from mouse bone marrow
Plasmid DNA Purification
Genomic DNA isolation from cells and tissues
RNA extraction from cells and tissues and reverse transcription
ELISA assay
Protein Extraction and Western Blotting
Cloning Techniques
RT-PCR and Real Time PCR
Bacterial Transformation
Microbioly Tecniques
Lentiviral Vector Production, titration, Lentivirus – Mediated Transduction
Mouse manipulation, practical skills about animal breeding and handling of mice colonies
Phage biopanning
COMPUTER KNOWLEDGE: Microsoft Office (Word, Excel, Power Point), DNAman, Adobe Photoshop, GenoPro, SigmaPlot, MiniTab softwares
POSTERS
Michienzi S., Piersanti S.,.Funari A., Remoli C., Cersosimo S., Costa R., Saggio I., Bianco P., Riminucci M., Phosphodiesterase-mediated adaptation to Gs-alpha mutations is developmentally regulated in embryonic and post-natal stem cells. 2nd Joint Meeting of the International-Bone-and-Mineral-Society/Australian-New-
Zealand-Bone-and-Mineral-Society, Sydney, AUSTRALIA, MAR 21-25, 2009. Int Bone & Mineral Soc; Australian & New Zealand Bone & Mineral Soc
Riminucci M., Saggio I., Remoli C., Cersosimo S., Di Consiglio A., Costa R., Bianco P. Fibrous dysplasia of bone-Transgenic Models of Desease and models of therapy. Poster, XVI Convention Telethon 2011, Riva Del Garda (Trento)
Costa R., Funari A., Remoli C., Piersanti S., Burla R., Riminucci M., Bianco P., SaggioI. Physiological and pathological roles of the stem cell marker, melanoma cell adhesion molecule MCAM/CD146. Poster, Biology and Molecular Medicine PhD symposium 2009 Sapienza University of Rome
PUBLICATIONS
Costa R., Scimmie transgeniche: che fare?, Scienza in rete, 19 agosto 2009
Costa R., La genomica per curare i tumori, Grande Enciclopedia medica 2011, Curcio Editore
Costa R., Intervista a Luigi Nicolais: uno scienziato prestato alla politica, Orizzonti biotecnologici n°1
Costa R., Rita Levi Montalcini e la scoperta del nerve growth factor, Orizzonti Biotecnologici n°3
Costa R., Riforma Gelmini: pareri a confronto. Intervista agli onorevoli Valentina Aprea e Walter Tocci, Orizzonti Biotecnologi n°4