Curriculum C. Merigliano

 

 

                                   

Birth date: 26/08/1986                                                        

Nationality: Italian      

           

Work address: Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Italy

e-mail: chiara.merigliano@uniroma1.it

Phone: +39 06 49912472     

 

 

EDUCATION AND TRAINING

 

×  December 2009: 1st level degree - Degree/Bachelor in Biology 110/110 cum laude - University of Rome, "Sapienza".

×  July 2011: 2nd cycle degree – Master/laurea magistralis in Genetics and Molecular Biology 110/110 cum laude - University of Rome, "Sapienza".

×  November 2011: Qualification as a Professional Biologist

×  February 2015: PhD in Genetics and Molecular Biology - University of Rome, "Sapienza".

 

RESEARCH AND PROFESSIONAL EXPERIENCE

 

-April 2015- November 2016: Postdoctoral fellow at University of Rome, "Sapienza". Supervisor: Dr Fiammetta Vernì. Research work: Exploiting the Drosophila model system to investigate the function of proteins involved in maintenance of genome stability

-January 2017-present: Postdoctoral fellow at University of Rome, "Sapienza". Supervisor: Professor Isabella Saggio. Research work: The lamin-interacting telomeric protein AKTIP in HGPS

 

TECHNICAL SKILLS, COMPETENCES

 

Mother tongue: Italian

Other language: English

Scientific skills: Good knowledge of formal genetics and cytology. Indirect immunofluorescence, RNA interference in cultured Drosophila and mammalian cells, basic molecular biology and biochemistry techniques (nucleic acids extraction, gel electrophoresis, PCR, RT-PCR, qPCR, cloning, Western blotting, co-immunoprecipitation). 

 

Computer skills:

·
Operating systems: Windows and Mac Os X

·Microsoft Office: Microsoft Word
, Microsoft Excel, 
Microsoft Power Point


·Adobe Suite: Adobe Photoshop CS6

·GraphPad Prism

·Image J

·Endnote X7

 

AWARDS, PARTECIPATION TO INTERNATIONAL MEETINGS AND COURSES

 

Award:

×  Doctoral fellowship from the University of Rome, "Sapienza" for the PhD programm in Genetics and Molecular Biology

×  Teresa Ariaudo Post-doctoral fellowship from Istituto Pasteur-Fondazione Cenci Bolognetti for the study of "The role of Twins (PP2A-B55) in the maintenance of Drosophila genome integrity"

×  Mention in 2015 by the Italian Genetic Association (AGI) for the PhD Thesis

 

International and National meetings:

 

×  04/2017 International Meeting on Laminopathies April 6-8, 2017 - Bologna - Italy

×  10/2015 EMBO Conference “The DNA damage response in cell physiology and disease”, Cape Sounio, Greece 5-9 October 2015. Poster entitled: “The role of Twins (PP2A-B55) in the maintenance of Drosophila genome integrity

×  09/2015 Conference of Italian Genetic Association (AGI), Cortona (Az), Italy 28-30 September 2015

×  09/2013 EMBO Drosophila Cell Cycle Workshop, Totnes, Devon, UK 12-16 September 2013. Poster entitled: Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells

×  09/2013 Conference of Italian Genetic Association (AGI), Cortona (Az), Italy 25-27 September 2013. Two posters entitled: “Protein phosphatase 2A (PP2A) is required for the maintenance of Drosophila chromosome integrity” and “Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells

×  09/2011 Conference AGI-SIBV-SIGA, Assisi, Italy 19/22 September 2011. Talk entitled : Protein phosphatase 2A (PP2A) is required for the maintenance of Drosophila chromosome integrity

 

 

PUBLICATIONS

 

×  Sugar and chromosome stability: clastogenic effects of sugars in vitamin b6-deficient cells. 
Merigliano C*, Marzio A*, Gatti M, Vernì F. PLoS Genet. 2014 Mar 20;10(3): e1004199  *Co-first Author

×  A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity. Merigliano C*, Marzio A*, Renda F, Somma MP, Gatti M, Vernì F. Genetics December 2016; doi: 10.1534/genetics.116.192781  *Co-first Author  

×  Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly. Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C et al. Cell Rep. 2017 Feb 14;18(7):1674-1686. doi: 10.1016/j.celrep.2017.01.054.

 

 

 

 

NEWS

2017/2018 Starting courses

Gene therapy, start 021017

 

Le nuove frontiere della biomedicina nella genetica e nelle neuroscienze, start 031017

 

Biologia delle cellule staminali e loro applicazioni, start 021017

2017/2018 Master on stem cells and genome editing

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