Birth date: 26/08/1986
Work address: Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Italy
Phone: +39 06 49912472
× December 2009: 1st level degree - Degree/Bachelor in Biology 110/110 cum laude - University of Rome, "Sapienza".
× July 2011: 2nd cycle degree – Master/laurea magistralis in Genetics and Molecular Biology 110/110 cum laude - University of Rome, "Sapienza".
× November 2011: Qualification as a Professional Biologist
× February 2015: PhD in Genetics and Molecular Biology - University of Rome, "Sapienza".
-April 2015- November 2016: Postdoctoral fellow at University of Rome, "Sapienza". Supervisor: Dr Fiammetta Vernì. Research work: Exploiting the Drosophila model system to investigate the function of proteins involved in maintenance of genome stability
-January 2017-present: Postdoctoral fellow at University of Rome, "Sapienza". Supervisor: Professor Isabella Saggio. Research work: The lamin-interacting telomeric protein AKTIP in HGPS
Mother tongue: Italian
Other language: English
Scientific skills: Good knowledge of formal genetics and cytology. Indirect immunofluorescence, RNA interference in cultured Drosophila and mammalian cells, basic molecular biology and biochemistry techniques (nucleic acids extraction, gel electrophoresis, PCR, RT-PCR, qPCR, cloning, Western blotting, co-immunoprecipitation).
· Operating systems: Windows and Mac Os X
·Microsoft Office: Microsoft Word , Microsoft Excel, Microsoft Power Point
·Adobe Suite: Adobe Photoshop CS6
× Doctoral fellowship from the University of Rome, "Sapienza" for the PhD programm in Genetics and Molecular Biology
× Teresa Ariaudo Post-doctoral fellowship from Istituto Pasteur-Fondazione Cenci Bolognetti for the study of "The role of Twins (PP2A-B55) in the maintenance of Drosophila genome integrity"
× Mention in 2015 by the Italian Genetic Association (AGI) for the PhD Thesis
International and National meetings:
× 04/2017 International Meeting on Laminopathies April 6-8, 2017 - Bologna - Italy
× 10/2015 EMBO Conference “The DNA damage response in cell physiology and disease”, Cape Sounio, Greece 5-9 October 2015. Poster entitled: “The role of Twins (PP2A-B55) in the maintenance of Drosophila genome integrity
× 09/2015 Conference of Italian Genetic Association (AGI), Cortona (Az), Italy 28-30 September 2015
× 09/2013 EMBO Drosophila Cell Cycle Workshop, Totnes, Devon, UK 12-16 September 2013. Poster entitled: Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells
× 09/2013 Conference of Italian Genetic Association (AGI), Cortona (Az), Italy 25-27 September 2013. Two posters entitled: “Protein phosphatase 2A (PP2A) is required for the maintenance of Drosophila chromosome integrity” and “Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells
× 09/2011 Conference AGI-SIBV-SIGA, Assisi, Italy 19/22 September 2011. Talk entitled : Protein phosphatase 2A (PP2A) is required for the maintenance of Drosophila chromosome integrity
× Sugar and chromosome stability: clastogenic effects of sugars in vitamin b6-deficient cells. Merigliano C*, Marzio A*, Gatti M, Vernì F. PLoS Genet. 2014 Mar 20;10(3): e1004199 *Co-first Author
× A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity. Merigliano C*, Marzio A*, Renda F, Somma MP, Gatti M, Vernì F. Genetics December 2016; doi: 10.1534/genetics.116.192781 *Co-first Author
× Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly. Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C et al. Cell Rep. 2017 Feb 14;18(7):1674-1686. doi: 10.1016/j.celrep.2017.01.054.