Curriculum R. Burla

 

February 19, 1983, Terni, Italy

Italian citizen

Department of Biology and Biotechnology "C.Darwin", Sapienza University of Rome, ex Institute of genetics, p.le Aldo Moro, 5, 00185, Rome, Italy

Phone number: 0649912472

E-mail: romina.burla@uniroma1.it

 

 

EDUCATION  

 

November 2012: PhD in Genetics and Molecular Biology, Dept of Biology and Biotechnology “C.Darwin”, University of Rome “La Sapienza” . PhD thesis title “Characterization of AKTIP, a new protein involved in human DNA replication and telomere metabolism”.

Group Leader: Prof. Isabella Saggio

April 2008: Master Degree in Genetics and Molecular Biology

Score 110/110 cum laude

Dept. of Genetics and Molecular Biology, University “La Sapienza”, Rome

Master Degree Thesis title: “Analysis by RNA interference of human gene AKTIP”

Group Leader: Prof. Isabella Saggio

February 2006: University Degree in Biological Sciences

Score: 110/110 cum laude

Dept. of Genetics and Molecular Biology, University “La Sapienza”, Rome

Degree Thesis title: “Use of lentivectors to mediate RNA interference of endogen genes in mammalian cells ”

Group Leader: Prof. Isabella Saggio

July 2002: Maturità scientifica PNI (High School Degree)

Score 100/100

Liceo “Galileo Galilei”, Terni, Italy

 

PROFESSIONAL EXPERIENCES

May 2014-present: postdoctoral research activity in the field of telomere metabolism and replication and aging related processes in mammalian cells. Dept of Biology and Biotechnology “C. Darwin”, Sapienza, University of Rome. Group leader I.Saggio.

May 2012: Research scolarship of Pasteur Institute-Fondazione Cenci Bolognetti (Teresa Ariaudo). in the field of telomere metabolism and replication and aging related processes in mammalian cells. Dept of Biology and Biotechnology “C. Darwin”, Sapienza, University of Rome. Group leader I.Saggio.

November 2011-present: postdoctoral research activity in the field of telomere metabolism and replication and aging related processes in mammalian cells. Dept of Biology and Biotechnology “C. Darwin”, Sapienza, University of Rome. Group leader I.Saggio.

2010-Present: Partecipation in AIRC founded project: “ Identification and characterization of Drosophila telomere capping proteins”.

2009-present: : Partecipation in european research project: “ Braincav”.

2008-2012: post-lauream training activity in the field of telomere metabolism and aging in mammalian cells. Dept of Biology and Biotechnology “C. Darwin”, Sapienza, University of Rome. Group leader I.Saggio.

2005-2008: Student training in the laboratory of Gene Therapy at the Unversity of Rome "La Sapienza", Department of Genetics and Molecolar Biology. Group leader: Prof. Isabella Saggio.

Research work: analysis of  proteins involved in DNA damage checkpoint,  Telomere metabolism and DNA damage repair.

 
2005/2006: Scholarship at the structure of Didactic Labs of the Department of Animal and Human Biology (BAU) of the University of Rome “La Sapienza”

 

2004/2005: Scholarship at the structure of Didactic Labs of the Department of Animal and Human Biology (BAU) of the University of Rome “La Sapienza”

 

LABORATORY SKILLS

Protein Extraction

Western Blotting

Lentivirus – Mediated Transduction

Cell Cultures

Cell Transfection

Bacterial Transformation

Microbioly Tecniques

RT-PCR

Real Time PCR

RNA extraction from cells and tissues and retrotranscription

Cloning Techniques

Plasmid DNA Purification (Maxiprep, Midiprep, Miniprep)

Genomic DNA isolation from cells and tissues

Cytological Preparation and analysis

FISH

COMPUTER KNOWLEDGE


Microsoft Word
Microsoft Excel
Microsoft Power Point
Adobe Photoshop 6.0
Microsoft Internet Explorer

GeneAmp700

WinMDI

Primer Express

DNAMan

Scion Image

 

 

FOREIGN LANGUAGES

English

 

POSTERS

Burla R., Caruso P., Piersanti S., Remoli C., Cundari E., Saggio I. Knock down of ATM and ATR induces p53 displacement from centrosomes in human primary cells.

Poster, FISV 2007 IX annual congress. Riva del Garda, Italy. (September 2007)

 

Caruso P., Burla R., Martina Y., Piersanti S., Remoli C., Saggio I. Adenovirus-induced activation of the human prion.

Poster, FISV 2007 IX annual congress. Riva del Garda, Italy. (September 2007)

 

Burla R., Carcuro M., Raffa G.D., Galati A., Cacchione S., Crescenzi M., Cenci G., Ciapponi L., Gatti M., Saggio I. AKTIP, a new lamin interacting protein is involved in telomere metabolism and DNA replication. Poster, ABCD 2011 Congress, Ravenna, Italia (8-10 Settembre 2011)

 

Burla R., Carcuro M., Raffa G.D., Galati A., Cacchione S., Crescenzi M., Cenci G., Ciapponi L., Gatti M., Saggio I. AKTIP, a new lamin interacting protein is involved in telomere metabolism and DNA replication. Presentazione orale, Joint Meeting AGI-SIBV-SIGA, Assisi, Italia (19-22 Settembre 2011)


Stefania Piersanti, Valerio Licursi, Catarina Brito, BURLA R., Alves Paula, Daniel Simao, Gina Devau, Carla Mottini, Rodolfo Negri, Enrico Tagliafico, Eric J. Kremer, Isabella Saggio (2014). High Throughput Comparative Analysis of the Response of Human and Nonhuman Primate Neurons To Viral Vectors. In: 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). Washington, DC, MAY 21-24, 2014, vol. 22, p. S192-S192, doi: 10.1038/mt.2014.6444


BURLA R., Mariateresa Carcuro, Grazia Raffa, Alessandra Galati, Domenico Raimondo, Angela Rizzo, Mattia la Torre, Emanuela Micheli, Laura Ciapponi, Giovanni Cenci, Enrico Cundari, Antonio Musio, Annamaria Biroccio, Stefano Cacchione, Maurizio Gatti, Isabella Saggio (2014). AKTIP, an E2 variant enzyme that interacts with lamin, is required for correct telomere maintenance. In: EMBO Meeting, Telomeres, Telomerase and Disease, oral presentation. Brussels, Belgium, 30 April – 4 May, 2014


BURLA R., Mariateresa Carcuro, Mattia La Torre, Elena Di Matteo, Grazia D. Raffa, Alessandra Galati, Domenico Raimondo, Laura Ciapponi, Giovanni Cenci, Enrico Cundari, Stefano Cacchione, Maurizio Gatti, and Isabella Saggio (2013). AKTIP, an E2 variant enzyme that interacts with lamin and protects mammalian telomeres from replicative damage. In: Telomeres & Telomerase Cold Spring Harbor Laboratory Meeting. selected talk. Cold Spring Harbor, NY, USA., April 30 - May 4, 2013

 

BURLA R., Mariateresa Carcuro, Mattia la Torre, Elena Di Matteo, Grazia D. Raffa, Alessandra Galati, Domenico Raimondo, Laura Ciapponi, Giovanni Cenci, Enrico Cundari, Stefano Cacchione, Maurizio Gatti and Isabella Saggio (2013). AKTIP, an E2 variant enzyme that interacts with lamin and protects mammalian telomeres from replicative damage. In: The Progeria Research Foundation scientific workshop. Bethesda, MD, USA, April 24 – 26, 2013

 

 PUBLICATIONS

BURLA R., M Carcuro, G.D. Raffa, A. Galati, D. Raimondo, A Rizzo, M. La Torre, E. Micheli, L. Ciapponi, G. Cenci, E. Cundari, A. Musio, A. Biroccio, S. Cacchione, M. Gatti, I. Saggio (2015). AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance. PLOS GENETICS, vol. 11; p. e1005167-e1005167, ISSN: 1553-7390, doi: 10.1371/journal.pgen.1005167

 

G. Cenci, L. Ciapponi, M. Marzullo, G.D. Raffa, P. Morciano, D. Raimondo, BURLA R., I. Saggio, M. Gatti (2015). The analysis of pendolino (peo) mutants reveals differences in the fusigenic potential among Drosophila telomeres. PLOS GENETICS, vol. 11; p. e1005260-e1005260, ISSN: 1553-7404, doi: 10.1371/journal.pgen.1005260


Piersanti S, Burla R, Licursi V, Brito C, La Torre M, Alves PM, Simao D, Mottini C, Salinas S, Negri R, Tagliafico E, Kremer EJ, Saggio I. (2014). Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups.PONE, 2015.

 

Caruso P, Burla R, Piersanti S, Cherubini G, Remoli C, Martina Y, Saggio I. Prion expression is activated by Adenovirus 5 infection and affects the adenoviral cycle in human cells. Virology. 2009.

 

Cherubini G, Naim V, Caruso P, Burla R, Bogliolo M, Cundari E, Benihoud K, Saggio I, Rosselli F. The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. Nucleic Acid Research. 2011.

 

NEWS

2017/2018 Master on stem cells and genome editing

A new international Master to work in the field of stem cells, gene therapy and tissue engineering. infos www.masterustem.it

Get a PhD fellowship

Send your CV to Isabella Saggio Infos

Bando Erasmus 2017

Become a science journalist

BrainVectors: Saggiolab activity on gene therapy vectors is financed by a EU international project

Saggiolab project selected for funding by PRF USA

Telethon to Saggiolab on progerias

Stoccolma a Roma: MasterSGP science metablog

How to get an International Degree - DDIF

Go here.

Get a fellowship for your DDIF in France. Go here.

Follow MasterSGP tweets