What we do - research




Saggiolab projects


-Gene therapy vectors

In the years we have been dealing with different viruses, including AAV, lentivirus, adenovirus and humanized phages. We use viral vectors for gene correction and disease modeling. Along with this we have been studying the properties of these viral vectors to understand their biology and possibly to design their amelioration.


-Telomeres and lamins in natural and pathological aging

We have characterized a new telomeric gene interacting with lamins named AKTIP. AKTIP properties put it at the crossroad of central aspects of human metabolism including DNA replication, nuclear architecture, telomeropathies, laminopathies and cancer.  We’re studying the implication of this gene in the different metabolic pathways by in tube and in vivo analyses.





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2017/2018 Starting courses

Gene therapy, start 021017


Le nuove frontiere della biomedicina nella genetica e nelle neuroscienze, start 031017


Biologia delle cellule staminali e loro applicazioni, start 021017

2017/2018 Master on stem cells and genome editing

A new international Master to work in the field of stem cells, gene therapy and tissue engineering. infos www.masterustem.it


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BrainVectors: Saggiolab activity on gene therapy vectors is financed by a EU international project

Saggiolab project selected for funding by PRF USA

Telethon to Saggiolab on progerias

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